Prof. Ilkay YILDIZ, Ph.D. (Former Member)

URL : http://80.251.40.59/pharmacy.ankara.edu.tr/iyildiz/
Email : iyildiz@pharmacy.ankara.edu.tr
Tel : + 90 (312) 203 30 69

Eğitim ve Yönetim Geçmişi

July 1986: B. Sc. at Ankara University, Faculty of Pharmacy
April 1989: M. Sc. degree at Ankara University Faculty of Pharmacy Department of Pharmaceutical Chemistry
July 1995: Ph.D. at University of Ankara, Faculty of Pharmacy Department of Pharmaceutical Chemistry
Supervisor: Prof. Dr. Ismail Yalcin
May 1996: Assistant Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry
November 1998: Associated Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry
March 2004: Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry

Bildiği Diller

  •  Turkish (Native Language)
  •  English (Fluent)
  •  German

Araştırma Alanları

  •  Computer-aided drug design (2D QSAR (Free-Wilson and Hansch analysis), 3D QSAR CoMFA, CoMSIA, HipHop, HypoGen, molecular modelling, conformational analysis, molecular dynamics)
  •  Computational Chemistry (Ab initio, DFT) 
  •  I am involved in some softwares such as Gaussian98, Sybyl, Macromodel, Maestro, Cerius4.10, Catalyst 4.10, APOLLO, PrGen, FlexS, SEAL, HyperChem, ChemDraw. I can use Unix, Windows 98 and Macintosh.
  •  Microbiological, Antitumoral, Antiviral, and Antioxidant activities
  •  Structure Analysis (IR, 1H NMR, Mass) and Synthesis of heterocyclic compounds
  •  HPLC

İş Deneyimi

1986-1996: I worked at Ankara University, Faculty of Pharmacy Department of Pharmaceutical Chemistry as research assistant in various subjects given below:

  •  Instrumental methods (UV, IR, NMR, Mass)
  •  Pharmacopoeia analysis
  •  Crystallization, distillation, extraction, chromatography (TLC, Column chromatography)
  •  Qualitative and Quantitative Drug Analysis
  •  Organic Chemistry, Synthesis of drug

Since May 1996: I have been lecturing to B.Sc., M.Sc. and Ph. D. students at Ankara University Faculty of Pharmacy Department of Pharmaceutical Chemistry

Doktora Sonrası Çalışmalar

  • 2000-2002 Visitor professor at Emory University, Department of Chemistry (Fellowships from TUBITAK and Emory Emerson Center)
  •  DFT studies on Taxol Biosynthesis 
  •  Molecular modelling of NMDA Antagonists

Danışman olunan Master Tezleri

  • Tugba ERTAN, 2005, "The Synthesis of Possible Metabolites, Structure Elucidation, Antimicrobial Activity and Molecular Modelling of Some New 2-Phenyl/benzylbenzoxazole derivatives"

Yayın Kurulu Üyelikleri

  •  Journal of Faculty of Pharmacy of Ankara University , Editorial Assistant (2002-Present)

Sempozyum ve Toplantı Organizasyonları

  •  ISOPS 7th International Symposium on Pharmaceutical Sciences, Social Committee, June 24-27, 2003, Ankara.
  •  Member of the Organizing Committee of the “15th European Symposium on Quantitative Structure-Activity Relationships”, Istanbul, 05-10 September 2004.
  •  Member of the Organizing Committee of the "Workshop on Computer Aided Drug Design & Development", Istanbul-TURKEY, February 02-05, 2007.
  •  Member of the Organizing Committee of “6th AFMC International Medicinal Chemistry Symposium", Istanbul-TURKEY, July 08-11, 2007.

Üyelikler

  •  Ankara Chamber of Pharmacists
  •  Turkish Association of Pharmaceutical and Medicinal Chemistry
  •  Development Association of Ankara University, Faculty of Pharmacy
  •  Computer Aided Drug Design and Development Society (CADD&D Society) in Turkey

Orijinal Yayınlar

  • 49
    ERTAN-BOLELLI, T., YILDIZ, I., OZGEN-OZGACAR, S., "Synthesis, Molecular Docking and Antimicrobial Evaluation of Novel Benzoxazole Derivatives", Med. Chem. Res., 25, 553-567 (2016). DOI: 10.1007/s00044-015-1499-1 [tüm metin]
  • 48
    ATAEI, S., YILMAZ, S., ERTAN-BOLELLI, T., YILDIZ, I., "Generated 3D-Common Feature Hypotheses Using the HipHop Method For Developing New Topoisomerase I Inhibitors", Archiv der Pharmazie, 348(7), 498-507, (2015). DOI:10.1002/ardp.201500045 [tüm metin]
  • 47
    AKI-YALCIN, E., ERTAN-BOLELLI, T., TASKIN-TOK, T., OZTURK, O., ATAEI, S., OZEN, C., YILDIZ, I., YALCIN, I., "Evaluation of Inhibitory Effects of Benzothiazole and 3-Amino-benzothiazolium Derivatives on DNA Topoisomerase II by Molecular Modeling Studies", SAR and QSAR in Environmental Research, 25(8), 637-649, (2014). doi:10.1080/1062936X.2014.923039 [tüm metin]
  • 46
    ERTAN-BOLELLI, T., MUSDAL, Y., BOLELLI, K., YILMAZ, S., AKSOY, Y., YILDIZ, I., AKI-YALCIN, E., YALCIN, I., “Synthesis, Biological Evaluation of 2-Substituted-5-(4-nitrophenylsulfonamido) benzoxazoles as Human GST P1-1 Inhibitors and Description of the Binding Site Features”, ChemMedChem,9(5), 984-992, (2014). doi:10.1002/cmdc.201400010 [tüm metin]
  • 45
    YILMAZ, S., ALTINKANAT-GELMEZ, G., BOLELLI, K., GUNESER-MERDAN, D., OVER-HASDEMIR, M. U., YILDIZ, I., AKI-YALCIN, E., YALCIN, I., “Pharmacophore Generation of 2-Substituted Benzothiazoles as AdeABC Efflux Pump Inhibitors in A. baumannii”, SAR and QSAR in Environmental Research, 25(7), 551-563, (2014). doi:10.1080/1062936X.2014.919357 [tüm metin]
  • 44
    MARY, Y. S., JOJO, P. J., PANICKER, C. Y., VAN ALSENOY, C., ATAEI, S., YILDIZ, I., "Quantum mechanical and spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations of 2-(phenoxymethyl)benzimidazole", Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 125, 12-24, (2014). doi:10.1016/j.saa.2014.01.068 [tüm metin]
  • 43
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., ERTAN-BOLELLI, T., YILDIZ, I., "Quantum mechanical and spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations of 5-nitro-2-phenylbenzoxazole", Journal of Molecular Structure, 1063, 16-29, (2014). Doi: 10.1016/j.molstruc.2014.01.018 [tüm metin]
  • 42
    MARY, Y. S., JOJO, P. J., PANICKER, C. Y., VAN ALSENOY, C., ATAEI, S., YILDIZ, I., "Theoretical investigations on the molecular structure, vibrational spectra, HOMO–LUMO and NBO analysis of 5-chloro-2-((4-chlorophenoxy)methyl)benzimidazole", Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 122, 499-511, (2014). Doi: 10.1016/j.saa.2013.11.025 [tüm metin]
  • 41
    ZILIFDAR, F., ALPER-HAYTA, S., YILMAZ, S., KAPLAN-OZEN, C., FOTO, E., AYDOGAN, Z., YILDIZ, I., AKI, E., YALCIN, I., DIRIL, N., "Genotoxic potentials and eukaryotic DNA topoisomerase I inhibitory effects of some benzoxazine derivatives", Med. Chem. Res., 23(1), 480-486, (2014). DOI: 10.1007/s00044-013-0658-5 [tüm metin]
  • 40
    YILMAZ, S., YALCIN, I., KAYNAK-ONURDAG, F., OZGEN, S., YILDIZ, I., and AKI, E., "Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles", Croat. Chem. Acta, 86(2), 223-231, (2013). Doi: 10.5562/cca2064 [tüm metin]
  • 39
    CAN, A., YILDIZ, I., GUVENDIK, G., "The determination of toxicities of sulphonylurea and phenylurea herbicides with quantitative structure–toxicity relationship (QSTR) studies", Environmental Toxicology and Pharmacology, 35(3), 369-379, (2013). Doi: 10.1016/j.etap.2013.02.001 [tüm metin]
  • 38
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., YILMAZ, S., YILDIZ, I., AKI, E., "Quantum mechanical and spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations of 2-(p-nitrobenzyl) benzoxazole", Journal of Molecular Structure, 1046, 92-100, (2013). Doi: 10.1016/j.molstruc.2013.04.044 [tüm metin]
  • 37
    KAPLAN-OZEN, C., TEKINER-GULBAS, B., FOTO, E., YILDIZ, I., DIRIL, N., AKI, E., YALCIN, I., "Benzothiazole derivatives as human DNA topoizomerase IIα inhibitors", Med. Chem. Res., 22(12), 5798-5808, (2013). DOI: 10.1007/s00044-013-0577-5 [tüm metin]
  • 36
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., BOLELLI, K., YILDIZ, I., AKI, E., "Vibrational spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations and computational study of 5-nitro-2-(4-nitrobenzyl) benzoxazole", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 102, 99-113, (2013). doi:10.1016/j.saa.2012.09.032 [tüm metin]
  • 35
    TASKIN, T., YILMAZ, S., YILDIZ, I., YALCIN, I., AKI, E., "Insight into eukaryotic topoisomerase II-inhibiting fused heterocyclic compounds in human cancer cell lines by molecular docking", SAR and QSAR Environmental Research, 23(3-4), 345-355, (2012). Doi:10.1080/1062936X.2012.664560 [tüm metin]
  • 34
    MARY, Y.S., RAJU, K., ERTAN-BOLELLI, T., YILDIZ, I., NOGUEIRA, H.I.S., "FT-IR, FT-Raman, surface enhanced Raman scattering and computational study of 2-(p-fluorobenzyl)-6-nitrobenzoxazole", Journal of Molecular Structure, 1012, 22-30, (2012). doi:10.1016/j.molstruc.2011.12.042 [tüm metin]
  • 33
    MARY, Y. S., PANICKER, C. Y., VARGHESE, H. T., RAJU, K., ERTAN-BOLELLI, T., YILDIZ, I., GRANADEIRO, C. M., NOGUEIRA, H. I. S., "Vibrational spectroscopic studies and computational study of 4-fluoro-N-(2’-hydroxy-4’-nitrophenyl)phenylacetamide", Journal of Molecular Structure, 994, 223–231, (2011). doi:10.1016/j.molstruc.2011.03.022 [tüm metin]
  • 32
    PANICKER, C. Y., VARGHESE, H. T., USHAKUMARI, L., ERTAN, T., YILDIZ, I., GRANADEIRO, C. M., NOGUEIRA, H. I. S., MARY, Y. S., "FT-IR, FT-Raman, SERS spectra and computational calculations of 4-ethyl-N-(2'-hydroxy-5'-nitrophenyl) benzamide", J. Raman Spectroscopy 41, 381–390, (2010). DOI: 10.1002/jrs.2471 [tüm metin]
  • 31
    PANICKER, C.Y., VARGHESE, H.T., RAJ, A., RAJU, K., ERTAN-BOLELLI, T., YILDIZ, I., TEMIZ-ARPACI, O., GRANADEIROF, C.M., NOGUEIRA, H.I.S., “IR, Raman and SERS spectra of 2-phenoxymethylbenzothiazole”, Spectrachimica Acta Part A, 74, 132–139, (2009). doi:10.1016/j.saa.2009.05.022 [tüm metin]
  • 30
    ERTAN, T., YILDIZ, I., TEKINER-GULBAS, B., BOLELLI, K., TEMIZ-ARPACI, O., OZKAN, S., KAYNAK, F., YALCIN, I., AKI, E., “Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents”, European Journal of Medicinal Chemistry, 44, 501–510, (2009). doi:10.1016/j.ejmech.2008.04.001 [tüm metin]
  • 29
    TEMIZ-ARPACI, Ö., YILDIZ, I., OZKAN, S., KAYNAK, F., AKI-SENER, E., YALÇIN, I., "Synthesis and biological activity of some new benzoxazoles" European Journal of Medicinal Chemistry, 43, 1423-1431, (2008). doi:10.1016/j.ejmech.2007.09.023 [tüm metin]
  • 28
    MARY, Y.S., VARGHESE, H.T., PANICKER, C.Y., ERTAN, T., YILDIZ, I., TEMIZ-ARPACI, O., “Vibrational spectroscopic studies and ab initio calculations of 5-nitro-2-(p-fluorophenyl) benzoxazole”, Spectrachimica Acta Part A, 71, 566–571, (2008). doi:10.1016/j.saa.2007.12.041 [tüm metin]
  • 27
    USHAKUMARI, L., VARGHESE, H.T., PANICKER, C.Y., ERTAN, T., YILDIZ, I.,“Vibrational spectroscopic studies and DFT calculations f 4-fluoro-N-(2-hydroxy-4-nitrophenyl)benzamide”, Journal of Raman Spectroscopy, 39, 1832-1839, (2008). DOI: 10.1002/jrs.2047 [tüm metin]
  • 26
    ARISOY, M., TEMIZ-ARPACI, O., YILDIZ, I., KAYNAK-ONURDAG, F., AKI, E., YALCIN, I., ABBASOGLU, U., “Synthesis, Antimicrobial Activity and QSAR Studies of 2,5-Disubstituted Benzoxazoles”, SAR and QSAR in Environmental Research, 19(5–6), 589–612, (2008). DOI: 10.1080/10629360802348738 [tüm metin]
  • 25
    YILDIZ, I., ERTAN, T., BOLELLI, K., TEMIZ-ARPACI, O.,YALCIN, I. AKI, E., "QSAR and Pharmacophore Analysis on Amides against Drug-Resistant S. aureus", SAR and QSAR in Environmental Research, 19(1-2), 101-113, (2008). DOI: 10.1080/10629360701844159 [tüm metin]
  • 24
    ALPER-HAYTA, S., ARISOY, M., TEMIZ-ARPACI, Ö., YILDIZ, I., AKI, E., ÖZKAN, S., KAYNAK, F., "Synthesis, Antimicrobial Activity, Pharmacophore Analysis of Some New 2-(Substitutedphenyl/ benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles", European Journal of Medicinal Chemistry, 43(11), 2568-2578, (2008). doi:10.1016/j.ejmech.2007.12.019 [tüm metin]
  • 23
    AMBUJAKSHAN, K.R., MADHAVAN, V.S., VARGHESE H.T., PANICKER C.Y., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., YILDIZ, I., "Vibrational Spectroscopic Studies and ab initio Calculations of 5-Methyl-2-(p-methylaminophenyl)benzoxazole", Spectrochim Acta A Mol Biomol Spectrosc., 69(3), 782-788, (2008). doi:10.1016/j.saa.2007.04.034 [tüm metin]
  • 22
    OKSUZOGLU, E., TEKINER-GULBAS, B., ALPER, S., TEMIZ-ARPACI, O., ERTAN, T., YILDIZ, I., DIRIL, N., SENER-AKI, E., YALCIN, I., "Some Benzoxazoles and Benzimidazoles as DNA Topoisomerase I and II Inhibitors", Journal of Enzyme Inhibition and Medicinal Chemistry, 23(1), 37-42, (2008). DOI: 10.1080/14756360701342516 [tüm metin]
  • 21
    OKSUZOGLU, E., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., EROGLU, H., SEN, G., ALPER, S., YILDIZ, I., DIRIL, N., AKI-SENER, E., YALCIN, I., "A Study on the Genotoxic Activities of Some New Benzoxazoles", Medicinal Chemistry Research, 16, 1–14, (2007). DOI 10.1007/s00044-007-9005-z [tüm metin]
  • 20
    TEKINER-GULBAS, B., TEMIZ-ARPACI, O., OKSUZOGLU, E., EROGLU, H., YILDIZ, I., DIRIL, N., AKI-SENER, E., YALCIN, I., "QSAR of Genotoxic Active Benzazoles", SAR and QSAR in Environmental Research, 18(3-4), 251–263, (2007). DOI: 10.1080/10629360701303966 [tüm metin]
  • 19
    ERTAN, T., YILDIZ, I., OZKAN, S., TEMIZ-ARPACI, O., KAYNAK, F., YALCIN, I., AKI-SENER, E., ABBASOGLU, U., "Synthesis and Biological Evaluation of New n-(2-Hydroxy-4(or 5)-nitro/ aminophenyl)benzamides and Phenylacetamides as Antimicrobial Agents", Bioorganic and Medicinal Chemistry, 15, 2032-2044, (2007). doi:10.1016/j.bmc.2006.12.035 [tüm metin]
  • 18
    AKBAY-YARPUZLU, A., UGUR, Y., NAZIKOGLU, A., ASAN, E., YILDIZ, I., "Investigation of Renal Histopathological Changes Due to HIV-RT Inhibitor 2-phenoxymethyl-5-chlorobenzimidazole Administration in Rats", Hacettepe J. Biol. & Chem., 35(1), 25-30, (2007). [tüm metin]
  • 17
    ANTO, P.L., PANICKER, C.Y., VARGHESE, H.T., PHILIP, D., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., YILDIZ, I., “Vibrational spectroscopic studies and ab initio calculations of 5-methyl-2-(p-fluorophenyl)benzoxazole”, Spectrochimica Acta Part A, 67, 744-749, (2007). Doi:10.1016/j.saa.2006.08.026 [tüm metin]
  • 16
    TEMİZ-ARPACI, Ö., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALCIN, İ., "3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method", QSAR and Molecular Modelling in Rational Design of Bioactive Molecules, Istanbul-Turkey, September 5-10, 2004, AKI-ŞENER, E., YALÇIN, İ. (Eds.), Başkent Publishing, Ankara, pp.396-398, (2006). [tüm metin]
  • 15
    ALPER-HAYTA, S., AKI-SENER, E., TEKINER-GULBAS, B., YILDIZ, I., TEMIZ-ARPACI, O., YALCIN, I., ALTANLAR, N., “Synthesis, Antimicrobial Activity and QSARs of New Benzoxazine-3-ones”, Eur. J. Med. Chem., 41(12), 1398-1404, (2006). [tüm metin]
  • 14
    TEMIZ-ARPACI, O., COBAN, T., TEKINER-GULBAS, B., CAN-EKE, B., YILDIZ, İ., AKI-SENER, E., YALCIN, I., ISCAN, M., “A Study on the Antioxidant Activities of Some New Benzazole Derivatives”, Acta Biol. Hungarica, 57(2), 201-209, (2006). [tüm metin]
  • 13
    TEKINER-GULBAS, B., TEMIZ-ARPACI, O., YILDIZ, I., AKI-SENER, E., YALCIN, I., “3D-QSAR Study on Heterocyclic Topoisomerase II Inhibitors using CoMSIA”, SAR and QSAR in Enviromental Research, 17(2), 121-132, (2006). [tüm metin]
  • 12
    UGUR, Y., AKBAY-YARPUZLU, A., NAZIKOGLU, A., ASAN, E., YILDIZ, I., KELES, S., "Investigating Toxic Effects of the HIV-RT Inhibitor 2-Phenoxymethyl-5-chloro-benzimidazole on Rat Liver", Turkish Journal of Medical Sciences , 35(1), 5-12, (2005). [tüm metin]
  • 11
    TEMIZ-ARPACI, O., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALÇIN, İ., “3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method”, Bioorganic&Medicinal Chemistry, 13, 6354–6359, (2005). [tüm metin]
  • 10
    TEMİZ-ARPACI, O., ÖZDEMİR, A., YALÇIN, İ., YILDIZ, İ., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some 5-[2-(Morpholin-4-yl)acetamido] and/or 5-[2-(4-Substituted piperazin-1-yl)acetamido]-2-(p-substituted phenyl)benzoxazoles", Arch. Pharm. Chem. Life Sci., 338, 105-111, (2005). [tüm metin]
  • 9
    YILDIZ-OREN, İ., TEKINER-GULBAŞ, B., TEMİZ-ARPACI, Ö., YALÇIN, İ., AKI-SENER, E., "Quantitative Structure-Activity Relationships using Comparative Molecular Field Analysis Studies on 2-(p-Substitutedbenzyl)-5-(substituted carbonylamino)benzaoxazoles as Antibacterial Agents against Staphylococcus aureus", Asian Journal of Chemistry, 16(3-4), 1359-1366, (2004). [tüm metin]
  • 8
    ÖREN-YILDIZ, İ., TEKİNER-GULBAŞ, B., YALÇIN, İ., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of New 2-[p-Substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles”, Arch. Pharm. Pharm. Med. Chem, 337, 402-410, (2004). [tüm metin]
  • 7
    PLEMPER, R.K., ERLANDSON, K.J., LAKDAWALA, A.S., SUN, A., PRUSSIA, A., BOONSOMBAT, J., AKI-ŞENER, E., YALÇIN, İ., YILDIZ, İ., TEMİZ-ARPACI, Ö., TEKİNER, B. P., LIOTTA, D., SNYDER, J.P., COMPANS, R.W., “A Target Site for Template-Based Design of Measles Virus Entry Inhibitors”, PNAS, 101(15), 5628-5633, (2004). [tüm metin]
  • 6
    ÖREN-YILDIZ, İ., YALÇIN, İ., AKI-ŞENER, E., UCARTURK, N., “Synthesis and Structure-Activity Relationships of New Antimicrobial Active Multisubstituted Benzazole Derivatives”, European Journal of Medicinal Chemistry, 39, 291-298, (2004). [tüm metin]
  • 5
    PINAR, A., YURDAKUL, P., YILDIZ, İ., TEMİZ-ARPACI, Ö., AÇAN, N.L., AKI-ŞENER, E., YALÇIN, İ.,”Some Fused Heterocyclic Compounds as Eukaryotic Topoisomerase II Inhibitors”, Biochemical and Biophysical Research Communications, 317, 670-674, (2004). [tüm metin]
  • 4
    YILDIZ-ÖREN, i., AKI-ŞENER, E., ERTAŞ, C., TEMİZ-ARPACI, Ö., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological activity of Some Substituted N-(2-hydroxy-4-nitrophenyl)benzamides and phenylacetamides as Possible Metabolites of Antimicrobial Active Benzoxazoles”, Turk J Chem., 28, 441-449, (2004). [tüm metin]
  • 3
    YALÇIN, İ., TEKİNER, B.P., ÖREN-YILDIZ, İ., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some Novel 2,6,7-trisubstituted-2H-3,4-dihydro-1,4-benzoxazin-3-one Derivatives”, Indian Journal of Chemistry, 42B, 905-909, (2003). [tüm metin]
  • 2
    AKBAY-YARPUZLU, A., YILDIZ, İ., TEMIZ-ARPACI, Ö., KARAGENÇ, N., AKI-ŞENER, E., YALÇIN, İ., “Adenosine Deaminase Inhibitor Activity of Some Benzoxazole, Benzimidazole, and Oxazolo(4,5-b)pyridine Derivatives”, XIII. Biotecnological Congress Proceedings Book, Çanakkale, 21-26, (2003).
  • 1
    LANKIN, D.C., GRUNEWALD, G.L., ROMERO, F.A., YILDIZ-OREN, I., SNYDER, J.P., “The NH---FC Dipole Orientation Effect for Pendant Exocylic CH(2)F”, Organic Letters, 4(21), 3557-3560, (2002). [tüm metin]

Sözlü Sunumlar

  • 8
    YILDIZ, I., ALPER, S., ERTAN, T., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., AKI-SENER, E., YALCIN, I., "Molecular Modeling Studies on Some Eucaryotic Topoisomerase II Enzyme Inhibitor Fused Heterocyclic Compounds", 6th AFMC International Medicinal Chemistry Symposium, Istanbul-TURKEY, July 08-11, 2007.
  • 7
    PINAR, A., YURDAKUL, P., TEMİZ-ARPACI, O., TEKİNER-GÜLBAŞ, B., YILDIZ, I., AKI-ŞENER, E., YALÇIN, İ., İLERİ, O., “Eukaryotic Topoisomerase II activity of some novel fused heterocyclic compounds”, 31st FEBS Congress, İstanbul, Turkey, 24-29 June 2006.
  • 6
    TEMİZ ARPACI, Ö., ÖKSÜZOĞLU, e., TEKİNER-GÜLBAŞ; B., ZAFER, B., YILDIZ, I., DİRİL, N., AKI-ŞENER, E., YALÇIN, İ., “Genotoxic activities and QSAR studies of some benzoxazoles and benzimidazoles”, QSAR 2006-12th International Workshop on Quantitative Structure-Activity Relationships in Enviromental Toxicology , Lyon, France, Abstract s O -67 , 8-12 May 2006.
  • 5
    AKI-ŞENER, E., YALÇIN, İ., ALPER-HAYTA, S., TEKİNER-GÜLBAŞ; B., TEMİZ ARPACI, Ö., YILDIZ, I., ALTANLAR, N., “Synthesis, antimicrobial activity and QSARs of New Benzoxazine-3-ones”, European Conference on the Reversal of Multidrug Resistance from Bacteria to Cancer Cells and Parasites, Budapest, Hungary, Abstracts OP-10, 22-25 April 2006.
  • 4
    YALÇIN, İ., AKI-ŞENER, E., YILDIZ, I., TEMİZ ARPACI, Ö., TEKİNER-GÜLBAŞ; B., “Research results incorporated on COST B16 Action from the year 2003 to 2006”, European Conference on the Reversal of Multidrug Resistance from Bacteria to Cancer Cells and Parasites, Budapest, Hungary, Abstracts OP-04, 22-25 April 2006.
  • 3
    YILDIZ, I., YALÇIN, İ., AKI-ŞENER, E., TEMİZ ARPACI, Ö., TEKİNER-GÜLBAŞ; B., “3D-QSAR Studies on Some Topoisomerase II Inhibitors” 3rd International Symposium Computational Methods In Toxicology &Pharmacology Integrating Internet Resources (CMTPI-2005), Shanghai, P.R: China, Abstract ORB-06, October 29th- November 1st, 2005.
  • 2
    AKI-ŞENER, E., YALÇIN, İ., YILDIZ, İ., TEMİZ-ARPACI, Ö., ALPER, S., ZAFER, B., “Studies on Pharmacophore Group Identification of Topoisomerase II Inhibitory Active Fused Heterocyclics Using CATALYST HipHop”, The European Cost Action B16 Symposium on Multidrug Resistance Reversal, Antalya, p19, 13-14 May, 2005.
  • 1
    AKI-ŞENER, E., YALÇIN, İ., YILDIZ, I., TEMİZ ARPACI, Ö., ZAFER, B., TEKİNER-GÜLBAŞ; B., ALPER, S., “3D-QSAR Studies of Topoisomerase II Inhibitors Using Catalyst ” Watoc`05, Modelling Structure and Reactivity 7th Congress of the World Association of Theoretically Oriented Chemists, Cape Town, South Africa, Abstract C12-5, 16-21 January 2005.

Poster Sunumlar

  • 8
    BOLELLİ, K., YALCIN, I., ERTAN, T., KAYNAK-ONURDAG, F., YILDIZ, I., TEMIZ-ARPACI, I., AKI-SENER, E., ABBASOGLU, U., "Synhtesis, Structure Elucidation and Microbiological Activity of Some New 2-[4-(4-Substitutedbenzamido)phenyl]benzothiazole Derivatives", Abst. P-61, 3rd International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-3), Antalya-TURKEY, October 16-21, 2007.
  • 7
    ALPER-HAYTA, S., ARISOY, M., TEMIZ-ARPACI, O., YILDIZ, I., AKI-SENER, E., KAYNAK-ONURDAG, F., "Synthesis and Antimicrobial Activity of Some New N-(2-Substitutedbenzoxazol-5-yl)-2-benzofurancarboxamides", Abst. P-11, 3rd International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-3), Antalya-TURKEY, October 16-21, 2007.
  • 6
    ARISOY, M., TEMIZ-ARPACI, O., KAYNAK-ONURDAG, F., YILDIZ, I., AKI-SENER, E., YALCIN, I., ABBASOGLU, U., "Synthesis and Antimicrobial Activity of Some Novel 2-(p-Substitutedbenzyl)-5-(2-substitutedacetamido)benzoxazole Derivatives", Abst. P-24, 3rd International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-3), Antalya-TURKEY, October 16-21, 2007.
  • 5
    ARISOY, M., TEMIZ-ARPACI, O., KAYNAK-ONURDAG, F., YILDIZ, I., AKI-SENER, E., YALCIN, I., ABBASOGLU, U., "Synthesis and Antimicrobial Activity of Some Novel N-(2-Substitutedbenzoxazol-5-yl)-2-(4-substitutedpiperazin-1-yl)acetamides", Abst. PC-29, 6th AFMC International Medicinal Chemistry Symposium (AIMECS 07), Istanbul-TURKEY, July 08-11, 2007.
  • 4
    YILDIZ, I., AKI-SENER, E., YALCIN, I., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., “3D-QSAR CoMSIA Study on Heterocyclic Topoisomerase II Inhibitors”, The 16th European Symposium on Quantitative Structure-Activity Relationships & Molecular Modelling, Mediterranean Sea, Italy, Abstract page 223, 10-17 September 2006.
  • 3
    ERTAN, T., YILDIZ, I., BOLELLI, K., TEMİZ-ARPACI, O., TEKİNER-GÜLBAŞ, B., AKI-ŞENER, E., YALÇIN, I., ABBASOGLU; U., “Synthesis and antibacterial activity of some 4-substituted-N-(2-hydroxy-5(or 6)-nitrophenyl)benzamide derivatives” International Symposium on Medicinal Chemistry Research and Development Kusadasi, Turkey, Abstract P81, September 28-October 1, 2005,.
  • 2
    TEMİZ-ARPACI, O., TEKİNER-GÜLBAŞ, B., YILDIZ, I., AKI-ŞENER, E., YALÇIN, I., ALTANLAR; N., “Synthesis and antifungal activity of some new 5-ethylsulphonyl-2-substitutedbenzoxazoles” Joint Meeting on Medicinal Chemistry, Vienna, Austria, June 20-23, 2005 Scientia Pharmaceutica Supplement 1. 73(2) S235, PO-177, 2005.
  • 1
    YILDIZ, İ., TEMİZ-ARPACI, Ö., TEKİNER-GÜLBAŞ, B., ERTAN, T., AKI-ŞENER, E., YALÇIN, I., “COMFA 3D-QSAR Studies on benzazole derivatives as eukaryotic topoisomerase II inhibitors” Joint Meeting on Medicinal Chemistry, Vienna, Austria, June 20-23, 2005 Scientia Pharmaceutica Supplement 1. 73(2) S234, PO-176, 2005.

Tam Metin Bildiri

  • 3
    AKI, E., YALCIN, I., YILDIZ, I., TEMIZ-ARPACI, O., BOLELLI, K., ERTAN-BOLELLI, T., DNA-Topoisomerase Inhibitory Activity of Some Heterocyclic Compounds and Their Structure-Activity Relationships", Med. Chem. Res., 19(Suppl.), S6, (2010). DOI 10.1007/s00044-010-9296-3 [tüm metin]
  • 2
    TEMİZ-ARPACI, Ö., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALCIN, İ., "3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method", QSAR and Molecular Modelling in Rational Design of Bioactive Molecules, Istanbul-Turkey, September 5-10, 2004, AKI-ŞENER, E., YALÇIN, İ. (Eds.), Başkent Publishing, Ankara, pp.396-398, (2006). [tüm metin]
  • 1
    AKBAY-YARPUZLU, A., YILDIZ, İ., TEMIZ-ARPACI, Ö., KARAGENÇ, N., AKI-ŞENER, E., YALÇIN, İ., “Adenosine Deaminase Inhibitor Activity of Some Benzoxazole, Benzimidazole, and Oxazolo(4,5-b)pyridine Derivatives”, XIII. Biotecnological Congress Proceedings Book, Çanakkale, 21-26, (2003).