Assist. Prof. Serap YILMAZ, Ph.D.

URL : https://personel.trakya.edu.tr/serapyilmaz/
Email : serapyilmaz@trakya.edu.tr
Tel : +90 (284) 235 40 10 / 2222

Educational and Administrative Background

2002-2006: B.Sc. at Ankara University Faculty of Pharmacy
2006-2008: M.Sc. degree at Ankara University Faculty of Pharmacy Department of Pharmaceutical Chemistry 
(Supervisor: Prof. Ismail YALCIN, Ph.D.)​
2008-2016: Ph.D. Student at Ankara University Faculty of Pharmacy Department of Pharmaceutical Chemistry
(Supervisor: Prof. Ismail YALCIN, Ph.D.)
2016-Present: Postdoctoral Fellow

Language Background

  •  Turkish (Native Language)
  •  English (Fluent)
  •  Spanish (Beginner Level)

Original Papers

  • 8
    ATAEI, S., YILMAZ, S., ERTAN-BOLELLI, T., YILDIZ, I., "Generated 3D-Common Feature Hypotheses Using the HipHop Method For Developing New Topoisomerase I Inhibitors", Archiv der Pharmazie, 348(7), 498-507, (2015). DOI:10.1002/ardp.201500045 [full text]
  • 7
    ERTAN-BOLELLI, T., MUSDAL, Y., BOLELLI, K., YILMAZ, S., AKSOY, Y., YILDIZ, I., AKI-YALCIN, E., YALCIN, I., “Synthesis, Biological Evaluation of 2-Substituted-5-(4-nitrophenylsulfonamido) benzoxazoles as Human GST P1-1 Inhibitors and Description of the Binding Site Features”, ChemMedChem,9(5), 984-992, (2014). doi:10.1002/cmdc.201400010 [full text]
  • 6
    YILMAZ, S., ALTINKANAT-GELMEZ, G., BOLELLI, K., GUNESER-MERDAN, D., OVER-HASDEMIR, M. U., YILDIZ, I., AKI-YALCIN, E., YALCIN, I., “Pharmacophore Generation of 2-Substituted Benzothiazoles as AdeABC Efflux Pump Inhibitors in A. baumannii”, SAR and QSAR in Environmental Research, 25(7), 551-563, (2014). doi:10.1080/1062936X.2014.919357 [full text]
  • 5
    ZILIFDAR, F., ALPER-HAYTA, S., YILMAZ, S., KAPLAN-OZEN, C., FOTO, E., AYDOGAN, Z., YILDIZ, I., AKI, E., YALCIN, I., DIRIL, N., "Genotoxic potentials and eukaryotic DNA topoisomerase I inhibitory effects of some benzoxazine derivatives", Med. Chem. Res., 23(1), 480-486, (2014). DOI: 10.1007/s00044-013-0658-5 [full text]
  • 4
    YILMAZ, S., YALCIN, I., KAYNAK-ONURDAG, F., OZGEN, S., YILDIZ, I., and AKI, E., "Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles", Croat. Chem. Acta, 86(2), 223-231, (2013). Doi: 10.5562/cca2064 [full text]
  • 3
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., YILMAZ, S., YILDIZ, I., AKI, E., "Quantum mechanical and spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations of 2-(p-nitrobenzyl) benzoxazole", Journal of Molecular Structure, 1046, 92-100, (2013). Doi: 10.1016/j.molstruc.2013.04.044 [full text]
  • 2
    MUSDAL, Y., ERTAN-BOLELLI, T., BOLELLI, K., YILMAZ, S., CEYHAN, D., HEGAZY, U., MANNERVIK, B., AKSOY, Y., "Inhibition of human glutathione transferase P1-1 by novel benzazole derivatives", Turk. J. Biochem., 37(4), 431-436, (2012). doi: 10.5505/tjb.2012.30301 [full text]
  • 1
    TASKIN, T., YILMAZ, S., YILDIZ, I., YALCIN, I., AKI, E., "Insight into eukaryotic topoisomerase II-inhibiting fused heterocyclic compounds in human cancer cell lines by molecular docking", SAR and QSAR Environmental Research, 23(3-4), 345-355, (2012). Doi:10.1080/1062936X.2012.664560 [full text]

Reviews

  • 1
    İŞGÖR, Y.G., YILMAZ, S., and ÖLGEN, S., “Kombinatoryal (Bütünleştirici) Kimya, Kombinatoryal Sentez Yöntem ve Teknolojileri, Kombinatoryal Kütüphaneler ve Yüksek Hızda Aktivite Tarama (YHAT)”, J. Fac. Pharm. Ankara, 37(1), 41-61, (2008). [in Turkish] [full text]

Oral Presentations

  • 7
    Ismail Yalcin*, Serap Yılmaz, Kayhan Bolelli, Ozum Ozturk, Esin Aki-Yalcin. Structure-Activity Relationship Analysis of Some Banzazoles as Topo II Enzyme Inhibitors, 5th International BAU Drug Design Congress, Bahçeşehir University, School of Medicine, Istanbul, Turkey, IS-18: p27, 19-21 October 2017.
  • 6
    Esin Aki-Yalcin*, Serap Yılmaz, Suzan Okten, Fatma Kaynak-Onurdag, Ismail Yalcin. Drug Design Studies of Some Heterocyclic Compounds Active in Hospital-Acquired Infections, 5th International BAU Drug Design Congress, Bahçeşehir University, School of Medicine, Istanbul, Turkey, IS-19: p28, 19-21 October 2017.
  • 5
    Egemen Foto, Fatma Zilifdar, Serap Yılmaz, İsmail Yalçın, Nuran Diril. Bir Seri 1,4-Benzoksazin-3-on Türevi Bileşiğin İn Vitro Anti-Kanser Etkileri ve Farmakofor Modellemesi, 23. Ulusal Biyoloji Kongresi, Gaziantep Üniversitesi, Gaziantep, Türkiye, 5-7 Eylül 2016.
  • 4
    Esin Akı Yalçın*, Serap Yılmaz, Kayhan Bolelli, Özüm Öztürk, Tuğba Ertan-Bolelli, İsmail Yalçın, The Role of Chemometrics in Computer Aided Drug Design Studies, 3rd International Conference on New Trends in Chemometrics and Applications (NTCA-2016), Side, Antalya, Turkey, IL-02: p4, May 25-28, 2016.
  • 3
    Esin Akı, İsmail Yalçın, İlkay Yıldız, Tugba Ertan-Bolelli, Kayhan Bolelli, Tugba Taşkın, Serap Yılmaz. Kemoterapötik Etkili Heterosiklik Bileşiklerin Bilgisayar Destekli İlaçTasarım Çalışmaları, Uluslararası Katılımlı 25. Ulusal Kimya Kongresi (UKK-25), Atatürk Üniversitesi, Erzurum, Türkiye, IL-009: p43, 27 Haziran - 02 Temmuz 2011.
  • 2
    Tugba Taskin-Tok, Esin Akı, Ismail Yalcin, Ilkay Yildiz, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yılmaz. Docking Studies of Topoisomerase II Inhibitors, Uluslararası Katılımlı 25. Ulusal Kimya Kongresi (UKK-25), Atatürk Üniversitesi, Erzurum, Türkiye, MS-013: p180, 27 Haziran - 02 Temmuz 2011.
  • 1
    Esin Akı, İsmail Yalçın, İlkay Yildiz, Tuğba Ertan-Bolelli, Kayhan Bolelli, Serap Yılmaz. Computer Aided Drug Design Studies on Chemotherapeutically Active Heterocyclic Compounds, Third International Meeting on Pharmacy & Pharmaceutical Sciences (IMPPS-3), Istanbul, Turkey, PL-2: p16, 9-12 June 2010.

Poster Presentations

  • 11
    Ozum Ozturk, Esin Akı-Yalçın, Tuğba Ertan-Bolelli, Kayhan Bolelli, Serap Yılmaz, İsmail Yalçın. Pharmacophore generation of neurokinin-1 receptor antagonists as antitumor agents, EACR-Sponsored 3rd Anticancer Agent Development Congress, Dokuz Eylül University, Izmir, Turkey, PP-094: p151, 18-19 May 2015.
  • 10
    Sanaz ATAEI, Serap YILMAZ, Ilkay YILDIZ, Tugba ERTAN-BOLELLI, Kayhan BOLELLI, Ozum OZTURK, Esin AKI-YALCIN, Ismail YALCIN. Molecular nDocking Studies of Some Benzazole Derivatives as DNA Topoisomerase I Inhibitors, 49th International Conference on Medicinal Chemistry (RICT-49), The Conference Center Nice Acropolis, Nice, France, HT006: p182, 3-5 July 2013.
  • 9
    Ozum OZTURK, Esin AKI-YALCIN, Tugba ERTAN-BOLELLI, Kayhan BOLELLI, Serap YILMAZ, Sanaz ATAEI, Ilkay YILDIZ, Ismail YALCIN. Common Feature Pharmacophore Generation of DNA Topoisomerase II Enzyme Inhibitors, 49th International Conference on Medicinal Chemistry (RICT-49), The Conference Center Nice Acropolis, Nice, France, HT094: p268, 3-5 July 2013.
  • 8
    Serap YILMAZ, Ismail YALCIN, Tugba ERTAN-BOLELLI, Kayhan BOLELLI, Ozum OZTURK, Ilkay YILDIZ, Esin AKI-YALCIN. Molecular Modeling and Docking Studies of AcrB Trimeric Multidrug Efflux Pumps, 1st International BAU-Drug Design Symposium 2013, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, P11: p63, 21-23 March 2013.
  • 7
    Ozum OZTURK, Esin AKI-YALÇIN, Tuğba ERTAN-BOLELLİ, Kayhan BOLELLİ, Serap YILMAZ, İlkay YILDIZ, İsmail YALÇIN. Docking Studies of Human Topoisomerase II Enzyme Inhibitors, 1st International BAU-Drug Design Symposium 2013, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, P12: p64, 21-23 March 2013.
  • 6
    Kayhan BOLELLI, Ismail YALCIN, Tugba ERTAN-BOLELLI, Serap YILMAZ, Ozum OZTURK, Ilkay YILDIZ, Esin AKI-YALCIN. Docking Studies of Glutathion S-Transferase (GST) Inhibitors, 1st International BAU-Drug Design Symposium 2013, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, P13: p65, 21-23 March 2013.
  • 5
    Emine Öksüzoğlu, Kayhan Bolelli, Tuğba Ertan-Bolelli, Serap Yılmaz, Nuran Diril. A Study on Mutagenic Effects of Novel Benzoxasole Derivative Compounds by Ames/Salmonella Microsomal Test System, 8. Uluslararası Katılımlı Türk Toksikoloji Derneği Kongresi (8.TTDK), Beldibi-Kemer, Antalya, Turkey, P67: p66, 15-18 Kasım 2012.
  • 4
    İlkay Yıldız, Serap Yılmaz, Sanaz Ataei, Esin Akı, İsmail Yalçın. Pharmacophore Analysis of Some Aromathecins as Topoisomerase I Inhibitor, 1st International Conference on New Trends in Chemometrics and Applications (NTCA-2011), Antalya, Turkey, PP-36: p63, 08-11 October 2011.
  • 3
    Kayhan Bolelli, Serap Yılmaz, İsmail Yalçın, İlkay Yıldız, Esin Akı. QSAR Analysis of Some 2-Substituted Benzothiazoles as Antibacterial Agents against Multidrug-Resistant Staphylococcus aureus, 1st International Conference on New Trends in Chemometrics and Applications (NTCA-2011), Side, Antalya, Turkey, PP-37: p64, 08-11 October 2011.
  • 2
    Serap Yılmaz, İlkay Yıldız, Esin Akı, İsmail Yalçın. 3D Pharmacophore Modelling of Some Fused Heterocyclic compounds as Topoisomerase II Inhibitor, 1st International Conference on New Trends in Chemometrics and Applications (NTCA-2011), Antalya PP-38: p65, 08-11 October 2011.
  • 1
    İlkay Yıldız, Sanaz Ataei, Serap Yılmaz, Egemen Foto, Tugba Ertan-Bolelli, Kayhan Bolelli, Nuran Diril, Esin Akı-Yalcin, İsmail Yalcin. Three-Dimensional Common-Feature Hypotheses on Benzoxazine Derivatives as Topoisomerase I Inhibitors, The 18th International Conference on Organic Synthesis (ICOS-18), Bergen, Norway, 377: p54, 1-6 August 2010.